53BP2 induces apoptosis through the mitochondrial death pathway
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منابع مشابه
Hydrogen peroxide induces apoptosis in HeLa cells through mitochondrial pathway.
Cervical cancer is the most common cancer amongst females in India and is associated with high risk HPVs, reactive oxygen species (ROS), and excessive inflammation in most cases. ROS in turn affects the expression of pro- and anti-apoptotic proteins. The objective of the present study was to elucidate the effect of hydrogen peroxide (H(2)O(2)) on apoptotic signaling molecules in vitro. HeLa cel...
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Isatin is an endogenous indole in mammalian tissues and fluids that is expected to have antitumor effects in human breast cancer cells. Human breast cancer cells (MCF-7) were exposed to isatin at various concentrations (0, 50, 100, 200 µmol/l) for 48 h. Apoptotic features were demonstrated by nuclei staining with Hoechst 33258 and flow cytometry. Bcl-2 and Bax mRNA were analyzed via reverse tra...
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ژورنال
عنوان ژورنال: Genes to Cells
سال: 2005
ISSN: 1356-9597,1365-2443
DOI: 10.1111/j.1365-2443.2005.00835.x